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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
26.36
Human Site:
T470
Identified Species:
41.43
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
T470
A
S
T
A
N
P
Q
T
P
V
E
Y
P
M
E
Chimpanzee
Pan troglodytes
XP_523815
451
50966
T399
V
D
S
P
D
D
S
T
L
S
E
S
A
N
Q
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
T470
A
S
T
A
N
P
Q
T
P
V
E
Y
P
M
E
Dog
Lupus familis
XP_537702
525
59107
T470
A
S
T
A
N
P
Q
T
P
V
E
Y
P
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
T470
A
S
T
A
N
P
Q
T
P
V
E
Y
P
M
E
Rat
Rattus norvegicus
P67999
525
59113
T470
A
S
T
A
N
P
Q
T
P
V
E
Y
P
M
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
P427
A
S
T
V
T
T
Q
P
P
V
E
Y
P
M
E
Chicken
Gallus gallus
P18652
752
84421
T457
K
R
C
I
H
K
T
T
N
M
E
Y
A
V
K
Frog
Xenopus laevis
P10666
629
71268
T438
K
R
C
V
H
K
G
T
N
M
E
Y
A
V
K
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
E460
K
S
K
R
D
P
S
E
E
I
E
I
L
M
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
S1123
S
W
R
K
T
R
A
S
W
R
H
F
C
L
L
Honey Bee
Apis mellifera
XP_395876
456
51514
Q403
I
L
E
D
M
Y
S
Q
P
R
V
I
N
A
R
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
Y480
M
K
A
T
R
R
K
Y
A
V
K
I
V
K
K
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
K433
R
S
A
I
S
P
A
K
T
P
Q
T
Q
F
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
G418
S
F
K
P
A
V
S
G
R
Q
C
I
A
N
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
13.3
100
100
N.A.
100
100
N.A.
73.3
20
20
26.6
N.A.
0
6.6
6.6
13.3
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
73.3
46.6
46.6
40
N.A.
26.6
6.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
40
0
14
34
7
0
14
0
7
0
0
0
27
7
7
% A
% Cys:
0
0
14
0
0
0
0
0
0
0
7
0
7
0
0
% C
% Asp:
0
7
0
7
14
7
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
7
0
0
0
0
7
7
0
67
0
0
0
40
% E
% Phe:
0
7
0
0
0
0
0
0
0
0
0
7
0
7
7
% F
% Gly:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
14
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
0
0
14
0
0
0
0
0
7
0
27
0
0
0
% I
% Lys:
20
7
14
7
0
14
7
7
0
0
7
0
0
7
20
% K
% Leu:
0
7
0
0
0
0
0
0
7
0
0
0
7
7
7
% L
% Met:
7
0
0
0
7
0
0
0
0
14
0
0
0
47
0
% M
% Asn:
0
0
0
0
34
0
0
0
14
0
0
0
7
14
0
% N
% Pro:
0
0
0
14
0
47
0
7
47
7
0
0
40
0
0
% P
% Gln:
0
0
0
0
0
0
40
7
0
7
7
0
7
0
7
% Q
% Arg:
7
14
7
7
7
14
0
0
7
14
0
0
0
0
14
% R
% Ser:
14
54
7
0
7
0
27
7
0
7
0
7
0
0
0
% S
% Thr:
0
0
40
7
14
7
7
54
7
0
0
7
0
0
0
% T
% Val:
7
0
0
14
0
7
0
0
0
47
7
0
7
14
0
% V
% Trp:
0
7
0
0
0
0
0
0
7
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
7
0
0
0
54
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _